CORONA Main Coronavirus thread

Heliobas Disciple

Heliobas Disciple

TB Fanatic
EMICT said:
[...]
Hopefully, they will come out with guidance along the lines of... 'If a patient presents with true flu like symptoms and tests negative for the flu, then this person automatically becomes a PUI and appropriate measures are taken to isolate and test further for nCoV'.
IMHO, that is the only way they are going to get a handle on it here in the US and provide proper guidance and reduce the spread. The "contact with know persons with nCoV or contact with persons from Wuhan" is already extinct for guidance.
Click to expand...

Totally agree. I'm afraid by the time they realize they need to do this it will be too late. It probably already is too late.

HD
 
Ragnarok

Ragnarok

On and On, South of Heaven
jward said:
Indeed it is often what finally gives...all I have read re: underlying medical on this patient is:
hope this helps...
BNO Newsroom
@BNODesk
27m

The only information is that he had a long-term underlying illness. He developed myalgia on January 29 and began having fever on January 31, when he was diagnosed with coronavirus. According to local media, he has now died of sudden heart failure.
Click to expand...

Almost every video I have seen of people rendering assistance to those who drop out includes chest compressions, so I would say the above is accurate
 
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Heliobas Disciple

Heliobas Disciple

TB Fanatic
jward said:
FluTrackers.com@FluTrackers
1m
Thailand has reported promising results in the treatment of the 2019 novel #coronavirus 2019-nCoV: combined lopinavir and ritonavir, + oseltamivir. Waiting for research results to confirm. https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/825629-discussion-thread-ii-2019-ncov-new-coronavirus?p=827244#post827244 h/t Treyfish #2019nCoV
Click to expand...

More on this:

www.scmp.com

Are cocktail therapies for flu and HIV the magic cure for coronavirus?

Weeks after the viral outbreak was first reported, a clear vaccine or treatment remains elusive. The desperate search for a cure has thrown up a range of recipes, from traditional Chinese medicine to home-grown boiled garlic.
www.scmp.com www.scmp.com
(fair use applies)

Could cocktail therapies for HIV and flu be the magic cure for the new coronavirus? Hospitals in Bangkok and Hangzhou put their combination remedies to the test
Eric Ng
Published: 2:24pm, 4 Feb, 2020
Updated: 2:24pm, 4 Feb, 2020

  • Hospitals in Bangkok, and the Zhejiang provincial capital of Hangzhou, are reporting successes in reducing viral loads
  • They are combining antiviral drugs with treatments for fighting the flu in “cocktail therapies” for treating the new coronavirus
Signs are emerging that a combination therapy involving cocktails of drugs meant for different ailments may be effective in combating the coronavirus outbreak around the world, with different hospitals from Bangkok to Zhejiang reporting cases of patients recovering from the disease.

Some Chinese companies are pulling out all the stops to research and produce antiviral drugs and other pharmaceuticals believed to be effective against the new coronavirus, even as clinical trials are still needed before efficacy can be scientifically proven.

A combination of anti-influenza medication Oseltamivir and HIV drugs Lopinavir and Ritonavir have been used on three patients with severe symptoms, according to Thai media reports, citing the Rajavithi Hospital’s director Somkiat Lalitwongsa, in Bangkok. One of the patients, a 71-year-old woman, showed signs of improvement 48 hours after being administered the cocktail of drugs, the reports said.

Similarly in China, three patients diagnosed with the new coronavirus infection recovered after taking Lopinavir and Ritonavir, according to a Monday stock exchange filing by Ascletis Pharma, citing the Henan provincial health commission. Ascletis, the Hong Kong-listed hepatitis drugs producer, said it has received requests from unnamed medical institutions and medical researchers to use its antiviral drug candidate ASC09 in combination with Ritonavir in clinical trials for coronavirus patients.

The new coronavirus, the second viral pandemic to emerge from China since the 2003 Sars outbreak, has infected more than 20,000 people, 99 per cent of which are found across all provinces in mainland China. The death toll stands at 427 cases, or just a little over 2 per cent of those infected, with two deaths outside the mainland while the remainder of the fatalities had been in China.

Weeks after the viral outbreak was first reported, a clear vaccine or treatment remains elusive. The desperate search for a cure has thrown up a range of recipes, from traditional Chinese medicine to home-grown boiled garlic.

Out of this mix, the combination of antiviral drugs and medication for treating flu appear to be showing the most potential. Combination therapy is not a novel concept, as it’s being increasingly used in the treatment of cancer.

“As there is no proven cure for the new coronavirus yet, existing antiviral drugs such as Oseltamivir has been used to treat patients with the coronavirus besides influenza,” said UOB Kay Hian senior health care analyst Carol Dou.

More than 20 confirmed cases of coronavirus patients had turned “negative” after taking Lopinavir and Ritonavir, Ascletis said, citing a preliminary survey by its medical team at several hospitals in Zhejiang province that the company didn’t identify.

A cocktail comprising Ritonavir – used for HIV treatments – and the antiviral drug AS09 showed a 62-fold reduction in viral load in coronavirus patients after 14 days of treatment, Ascletis said, citing a previous phase two clinical trial that was completed offshore, which the company did not specify.

To be sure, Ascletis “cannot guarantee that we will be able to obtain approval for, or ultimately market, the Ritonavir and ASC09 combination, successfully,” the Hangzhou-based company said, even though it has been “actively assisting” medical researchers to initiate clinical trials in coronavirus patients. The company’s stock, which has plunged 68 per cent since its initial public offering (IPO) in August 2018, fell by 17 per cent on Tuesday to an intraday low of HK$4.10.

Lopinavir and Ritonavir were developed by Chicago-based Abbvie for treating immunological diseases including HIV.

Ritonavir is not sold in China, and at least two companies are claiming to be making generic versions in the country. Ascletis claims it has developed China’s first generic version of Ritonavir and has applied last August to the National Medical Products Administration for permits to produce and market it.

China Health Group, a Beijing-based pharmaceutical company listed on Hong Kong’s GEM, claimed that its Wanquan Wante Xiamen Pharmaceutical affiliate is the sole Chinese company that has produced raw material for Lopinavir and Ritonavir, according to an exchange filing last Wednesday. An official at Wante said it had no licensing relationship with Abbvie, in a statement to South China Morning Post.

Still, Wante had applied to the government for permission to resume production of the materials, and China Health will invest in clinical research on producing and marketing the drug in China, according to the company’s statement. Wante soared 14-fold since its announcement about the coronavirus business opportunity.

Meanwhile, Hong Kong-listed Yichang HEC Changjiang Pharmaceutical, licensed by Swiss pharmaceutical giant Roche to produce the flu medication Oseltamivir – better known as Tamiflu – in China, has been doing brisk business.

Its sole distributor of the drug, Shanghai-listed Jointown Pharmaceutical Group, sold 1 billion yuan of the drug in January alone, with accumulated sales since September 2019 topping 1.5 billion yuan (US$214 million), according to its disclosure to the Shanghai Stock Exchange on Monday.

Antiviral drugs are not the only drug used for other diseases being tried on patients infected by the coronavirus.

Tongfang Kontafarma Holdings, a Hong Kong-listed producer of cement clinker, said its chloroquine phosphate – used for treating malaria – has been tested and proven to have “certain curative effect” in combating the coronavirus, according to its filing to the exchange, citing the Chinese Ministry of Industry and Information Technology (MIIT) and the Chongqing municipal government.

Tongfang said it was told by the authorities to “promptly resume” producing the pharmaceutical ingredient, even as other companies whad been barred from resuming operations at least until February 10, amid a general lockdown of facilities to observe a state-ordered quarantine of affected areas. Its production has resumed at Tongfang's subsidiary Chongqing Kangle Pharmaceutical, Tongfang said, without giving volume and financial details.

Tongfang shares closed the morning trading session up 51.5 per cent at 20 HK cents after surging as much as 135 per cent.
 
jward

jward

passin' thru
The annual ASM Biothreats conference convened Jan. 28-30. Anthony Fauci spoke at the Plenary Session “Biothreats: How Prepared are We?” in his first public address about the 2019 novel coronavirus (nCoV2019). The following is a summary of his talk, titled “Coronavirus Infections: More than Just the Common Cold.”

DrAlfredoTorres@DrAlfredoTorre1
https://twitter.com/DrAlfredoTorre1/status/1222512855297163269

Dr Tony Fauci #ASMbiothreats talking about the recent #coronavirus outbreak @ASMicrobiology @utmbhealth @utmbnews @ihii_utmb
View image on Twitter

17
7:32 AM - Jan 29, 2020 · Arlington, VA
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See DrAlfredoTorres's other Tweets




Eighteen years ago, the world experienced an unusual outbreak involving a new respiratory disease. Named for the pathology of the disease it caused, Sudden Acute Respiratory Syndrome Coronavirus (SARS-CoV) was eventually discovered as a new human pathogenic virus. Transparency was an issue as SARS cases mounted and the Chinese government tried to muffle the news (an issue that has been fortunately corrected with the nCoV2019 response). The local outbreak quickly became an international epidemic, thanks in part to global air travel. Panic from rumor and misinformation hurt people, communities, and the economy.

Infection control measures eventually brought the outbreak to an end. Twenty months after the SARS-CoV was sequenced, Phase I trials were already underway for a new SARS-CoV vaccine. At that time, this represented as the fastest turnaround time from microorganism identification to vaccine trial in people.

In 2012, a similar worldwide incident occurred. The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) also caused respiratory disease, traced to camels (which had acquired the virus from bats). This time, viral infection was associated with a higher case fatality rate. Unlike SARS, MERS has not disappeared and cases continue to occasionally reemerge. When not properly recognized, epidemics can crop up outside of the Middle East, as happened in South Korea in 2015.

Now the world is experiencing an outbreak from a third coronavirus, named 2019 Novel Coronavirus (though this name will certainly change as more is learned about the disease it causes). At first, cases were thought to have occurred from exposure in a fish market. We now know there were earlier cases and the market had simply provided amplification based on a crowded market.

Who is getting sick with nCoV2019? The disease is one predominantly observed in elderly, older persons. Only 2% of cases are young; only 25% of recognized cases have severe disease. The take-home message is that nCoV2019 is a very different case than with SARS.

Unfortunately, this couldn’t have happened at a worse time for China. The Lunar New Year is the largest mass transit event of people in the world every year. The country is trying to control viral transmission via quarantine, but with varying success.

After years of talk of a universal flu vaccine, it may be time to start talking about other universal vaccines—such as one for coronaviruses. With 3 outbreaks in 18 years, coronaviruses and the diseases they cause are not going away. Barney Graham of the NIH is leading the efforts to make a vaccine for the current outbreak.

The current nCoV2019 outbreak is an evolving problem, and events will change quickly in coming days, months and years. Stay up to date at ASM’s Coronavirus Resource page.
 
Seeker22

Seeker22

Has No Life - Lives on TB
Mark D said:
Anyone else come across the apparent "mistake" of real numbers being temporarily published on 26-Jan and again on 02-Feb??? Red numbers are SUSPECTED, yellow is CONFIRMED, green is RECOVERED, and black is DEAD.

"Apparently", these numbers we only up for a short time before the censors addressed the issue... Who knows.

26-Jan:
6acsu6M.jpg


02-Feb:
s40aRvV.jpg
Click to expand...

Is there a direct link to this please? The cool stuff link is old recipes.
 
Heliobas Disciple

Heliobas Disciple

TB Fanatic
www.scmp.com

‘Striking’ coronavirus mutations found in one family, scientists say

More work needed to determine impact of genetic changes on patients, according to researchers.
www.scmp.com www.scmp.com
(fair use applies)

‘Striking’ coronavirus mutations found within one family cluster, Chinese scientists say
Stephen Chen
Published: 11:30pm, 3 Feb, 2020 | Updated: 1:41am, 4 Feb, 2020

  • ‘More work needed’ to determine impact of genetic changes on patients
  • Case points to viral evolution in human-to-human transmission, researchers say
Chinese scientists say they have detected “striking” mutations in a new coronavirus that may have occurred during transmission between family members.

While the effects of the mutations on the virus are not known, they do have the potential to alter the way the virus behaves.

Researchers studying a cluster of infections within a family in the southern province of Guangdong said the genes of the virus went through some significant changes as it spread within the family.

Viruses mutate all the time, but most changes are synonymous or “silent”, having little effect on the way the virus behaves. Others, known as nonsynonymous substitutions, can alter biological traits, allowing them to adapt to different environments.

Two nonsynonymous changes took place in the viral strains isolated from the family, according to a new study by Professor Cui Jie and colleagues at the Institut Pasteur of Shanghai.

This case indicated “viral evolution may have occurred during person-to-person transmission”, they wrote in the paper published in the journal National Science Review on January 29.

“Close monitoring of the virus’s mutation, evolution and adaptation is needed,” they added.

Cui’s team also detected a total of 17 nonsynonymous mutations from cases around the country between December 30 and late January, they wrote.

But “we do not have an answer yet” on whether the new coronavirus is changing faster than Sars or other viruses, according to Shi Zhengli, a researcher at the Wuhan Institute of Virology, who was not involved in the study. Sars, or severe acute respiratory syndrome, mutated at the speed of 1 to 3 changes per thousand “sites” each year, according to previous studies.

Shi said that scientists still did not know the mutation speed of the new coronavirus because “most of the available [viral gene] sequences are not complete. They come in fragments.”

Sequencing entire genomes is time-consuming and expensive. The new coronavirus’ genes also have a total length of nearly 30,000 base pairs, longer than many other viruses, including its distant cousin Sars.

But on Saturday, the Zhejiang Provincial Centre for Disease Control and Prevention (Zhejiang CDC) said it was teaming up with tech giant Alibaba, which owns the South China Morning Post, to develop a new method of genome analysis using artificial intelligence to study the virus from patient samples.

The Zhejiang CDC said the new technology was expected to cut the sequencing time from several hours to about 30 minutes, allowing scientists to track mutations quicker and more precisely.

It is not clear yet what the mutations mean for patients. Qiu Haibo, a member of the national expert panel advising the government on the fight against the virus, said on Sunday that so far there was no evidence that mutations could cause “repeated infections”.

But theoretically, mutations can make recovered patients sick again and cheat existing detection methods because they target only a small segment of the viral genome.

A study led by University of Minnesota researcher Li Fang predicted that a single mutation at a specific spot in the genome could significantly increase the virus’s ability to bind with cells on the surface of the human respiratory system, according to their paper published in the Journal of Virology on January 29.
 
Heliobas Disciple

Heliobas Disciple

TB Fanatic
https://twitter.com/i/web/status/1224520887723905024
View: https://twitter.com/chenkan8201/status/1224520887723905024


Kan chen @chenkan8201
9:31 PM · Feb 3, 2020

According to the clinical experiences of a physician at the epicenter of #2019nCoV, it is the late-onset and sudden cytokine storm that kill many patients, not the infection resulted pneuminia.

Vixenbae @Vixenbae1
3h
Replying to@chenkan8201

What gene is activated due to the cytokine stimulus? And what is the biological effect?

Kan chen @chenkan8201
3h

Possible candidate sensors for ssRNA virus: TLR7, TLR8, RIG-1


shimi @shimi30809579
19m
Replying to @chenkan8201

It’s also what kill many people in the Spanish flu
 
Heliobas Disciple

Heliobas Disciple

TB Fanatic
Heliobas Disciple

Heliobas Disciple

TB Fanatic
STAY OUT OF PUBLIC BATHROOMS IN AIRPORTS AND HOSPITALS.

www.scmp.com

Scientists say deadly virus may live and spread in human faeces

The findings have prompted researchers to warn of possible faecel-oral transmission of the disease, in addition to transfer via respiratory droplets and contact.
www.scmp.com www.scmp.com
(fair use applies)

Coronavirus: scientists identify possible new mode of transmission in human faeces
Zhuang Pinghui
Published: 6:59pm, 2 Feb, 2020
Updated: 10:54pm, 2 Feb, 2020

  • Genetic traces of the new coronavirus have been found in the stool of patients being treated at a hospital in Shenzhen
  • The findings have prompted researchers to warn of possible faecel-oral spread of the disease, in addition to respiratory droplet transmission and contact
Chinese scientists have found traces of the new coronavirus in the faeces of some infected patients, possibly indicating an additional mode of transmitting the deadly disease.

Health authorities had previously thought the main ways the disease was spread was through respiratory droplet transmission and contact, including touching the face after exposure to a surface containing the virus. But new findings from Shenzhen Third People’s Hospital raise the possibility of faecel-oral transmission, after researchers found genetic traces of coronavirus in patients’ stool samples.

The presence of the 2019 coronavirus RNA, or ribonucleic acid – a molecule that carries genetic codes in some viruses – indicates the disease may live in faeces, the Shenzhen Health Commission said in a statement on Saturday. The results have echoed similar findings elsewhere, including in Wuhan, the epicentre of the virus outbreak, and the United States, with some scientists saying the research shows it was possible the virus was transmitted via human excrement.

Researchers at Shi Zhengli’s Laboratory at the Wuhan Institute of Virology, which is administered by the Chinese Academy of Sciences, found nucleic acids in stool samples and anal swabs from a group of coronavirus pneumonia patients in the city, according to a report from state news agency Xinhua.

The scientists concluded that the virus could be transmitted “to a certain degree” via facecal-oral transmission.

“Clinicians, especially gastroenterologists, should pay close attention to the atypical symptoms of pneumonia caused by new coronavirus infection, and take personal protection against vomitus and faeces,” they said.

Zhang Qiwei, a professor at the School of Public Health of the Southern Medical University, said it was highly likely that the patients’ faeces contained the live virus, even though it was RNA that was found.

The professor said it was possible the coronavirus might be transmitted via faeces. After entering the intestine and multiplying, it may then be excreted and come into contact with a person's hands, he said.

He also warned that the virus could be turned to vapour by the force of a toilet flushing, endangering people in the same room.

“Now disinfection of toilets may be on the agenda,” Zhang told the Beijing News. “Toilets used by patients with new coronary pneumonia or suspected patients need to be thoroughly disinfected and the restroom must be ventilated.”

Whether it is transmitted through the feces or re-transmitted via the formation of aerosols by virus-containing droplets, we need epidemiological investigation and research to further confirm Feng Luzhao

However, Feng Luzhao, a researcher with Chinse Centre for Disease Control and Prevention, said further investigation was needed to prove transmission through this method. He said the recent findings only indicated the virus could replicate and exist in the digestive tract.

“Whether it is transmitted through the feces or re-transmitted via the formation of aerosols by virus-containing droplets, we need epidemiological investigation and research to further confirm,” Feng said at a daily press conference held by the National Health Commission on Sunday.

The phenomena still served as a reminder of the importance of washing your hands frequently, Feng said.

Genetic traces of the new coronavirus have also been found in the stool of a 35-year-old man from the US who had recently travelled to Wuhan.

Doctors treating the man, the first confirmed case in the country, published details of their findings in the New England Journal of Medicine on Friday, though cautioned extrapulmonary detection of viral RNA does not necessarily mean the virus was present.

The clinical significance of coronavirus RNA outside the respiratory tract was unknown at this time, the doctors said.

Confirmed cases of coronavirus have now hit record daily highs, health officials in China say, and the virus has killed at least 305 people and infected more than 14,300 in the mainland.

In 2003, more than 320 residents in the Amoy Gardens housing estate in Hong Kong became infected with Severe acute respiratory syndrome (Sars), a type of coronavirus.

The World Health Organisation found the virus remained stable for up to four days in the faeces of infected people with diarrhoea. This contributed to a significant viral load being discharged into a broken sewage system that helped spread the disease.
 
Tristan

Tristan

Has No Life - Lives on TB
jward said:
The annual ASM Biothreats conference convened Jan. 28-30. Anthony Fauci spoke at the Plenary Session “Biothreats: How Prepared are We?” in his first public address about the 2019 novel coronavirus (nCoV2019). The following is a summary of his talk, titled “Coronavirus Infections: More than Just the Common Cold.”

See DrAlfredoTorres's other Tweets



Eighteen years ago, the world experienced an unusual outbreak involving a new respiratory disease. Named for the pathology of the disease it caused, Sudden Acute Respiratory Syndrome Coronavirus (SARS-CoV) was eventually discovered as a new human pathogenic virus. Transparency was an issue as SARS cases mounted and the Chinese government tried to muffle the news (an issue that has been fortunately corrected with the nCoV2019 response). The local outbreak quickly became an international epidemic, thanks in part to global air travel. Panic from rumor and misinformation hurt people, communities, and the economy.

Infection control measures eventually brought the outbreak to an end. Twenty months after the SARS-CoV was sequenced, Phase I trials were already underway for a new SARS-CoV vaccine. At that time, this represented as the fastest turnaround time from microorganism identification to vaccine trial in people.

In 2012, a similar worldwide incident occurred. The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) also caused respiratory disease, traced to camels (which had acquired the virus from bats). This time, viral infection was associated with a higher case fatality rate. Unlike SARS, MERS has not disappeared and cases continue to occasionally reemerge. When not properly recognized, epidemics can crop up outside of the Middle East, as happened in South Korea in 2015.

Now the world is experiencing an outbreak from a third coronavirus, named 2019 Novel Coronavirus (though this name will certainly change as more is learned about the disease it causes). At first, cases were thought to have occurred from exposure in a fish market. We now know there were earlier cases and the market had simply provided amplification based on a crowded market.

Who is getting sick with nCoV2019? The disease is one predominantly observed in elderly, older persons. Only 2% of cases are young; only 25% of recognized cases have severe disease. The take-home message is that nCoV2019 is a very different case than with SARS.

Unfortunately, this couldn’t have happened at a worse time for China. The Lunar New Year is the largest mass transit event of people in the world every year. The country is trying to control viral transmission via quarantine, but with varying success.

After years of talk of a universal flu vaccine, it may be time to start talking about other universal vaccines—such as one for coronaviruses. With 3 outbreaks in 18 years, coronaviruses and the diseases they cause are not going away. Barney Graham of the NIH is leading the efforts to make a vaccine for the current outbreak.

The current nCoV2019 outbreak is an evolving problem, and events will change quickly in coming days, months and years. Stay up to date at ASM’s Coronavirus Resource page.
Click to expand...


"only 25% of recognized cases have severe disease."

Whew! I was worried there for a bit. :rolleyes:
 
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jward

jward

passin' thru
P

Plain Jane

Just Plain Jane
Wow! This is not how to make friends.

Zerohedge

ZeroHedge - On a long enough timeline, the survival rate for everyone drops to zero
www.zerohedge.com www.zerohedge.com

Muslim Cleric Issues Fatwa Celebrating Coronavirus "Annihilation" Of Chinese People
Profile picture for user Tyler Durden
by Tyler Durden
Tue, 02/04/2020 - 03:30
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Authored by Paul Joseph Watson via Summit news,
While the media continues to fret about “racist” bat soup memes, a Muslim cleric just issued a fatwa celebrating the coronavirus outbreak and calling for the “annihilation” of Chinese people.

On January 23rd last month, Syrian jihadi cleric Abd Al-Razzaq Al-Mahdi celebrated the spread of coronavirus in China and urged Muslims to pray for Allah to “annihilate” the people of China.



“Al-Mahdi is a prominent cleric who is well respected by jihadi factions, and who is known for his sermons and fatwas, in which he encourages Muslims to take part in jihad and carry out attacks inside Russia,” reports MEMRI.
Click to expand...
Titled ‘Fatwas from the Land of Sham’ – Al-Mahdi was responding to a question from Muhammad Abu Nassir, who asked, “Is it permissible that we express our joy for what China is experiencing – the coronavirus and the death of the Chinese people?”
“Yes, yes we should express our joy and pray for their annihilation,” responded Al-Mahdi.
“They [the Chinese] have declared resounding war and they killed, slaughtered, imprisoned, and oppressed the Uyghurs and non-Uyghur Muslims. They are the enemies of Allah and are Buddhists and communists.”
Click to expand...
Al-Mahdi’s fatwa was issued via Telegram, but he is also apparently active on Twitter, which presumably permits jihadist fatwas yet just banned Zero Hedge for questioning the official story on the coronavirus outbreak.

Al-Mahdi’s fatwa is apparently not as newsworthy as the media’s primary obsession – patrolling “racist” bat soup memes.

There have been innumerable articles published over the last 10 days suggesting that the spread of bigotry in the form of criticism of Chinese people’s bizarre dietary habits is more concerning than the spread of the global coronavirus epidemic.

The fact remains; Whatever the source of the coronavirus (the source of both Ebola and SARS was bats), eating bats, dogs, pulling the intestines out of live frogs and dipping baby mice in sauce then chomping down on their wriggling bodies – is all objectively disgusting.
 
marsh

marsh

On TB every waking moment
Heliobas Disciple said:
According to the clinical experiences of a physician at the epicenter of #2019nCoV, it is the late-onset and sudden cytokine storm that kill many patients, not the infection resulted pneuminia.

It’s also what kill many people in the Spanish flu
Click to expand...

This does not make sense. As I understood it, this virus hits older adults, often with chronic disease conditions like Diabetes, high blood pressure/heart disease. The immune system in older people is degraded and often compromised with chronic disease. This is why the Spanish Flu hit healthy young people with the cytokine storm reaction. Why would there be a cytokine storm in the immunity suppressed? A cytokine storm, as I understand it, is an excessive immunity reaction. In addition, the virus supposedly causes a drop in blood pressure in serious cases, but high blood pressure was sited as a condition that was found to effect the initial group of patients.
 
bw

bw

Fringe Ranger
marsh said:
This does not make sense. As I understood it, this virus hits older adults, often with chronic disease conditions like Diabetes, high blood pressure/heart disease. The immune system in older people is degraded and often compromised with chronic disease. This is why the Spanish Flu hit healthy young people with the cytokine storm reaction. Why would there be a cytokine storm in the immunity suppressed? A cytokine storm, as I understand it, is an excessive immunity reaction. In addition, the virus supposedly causes a drop in blood pressure in serious cases, but high blood pressure was sited as a condition that was found to effect the initial group of patients.
Click to expand...

Two paths to the same result. In the young and healthy, the cytokine storm takes them out. In the old and immune-compromised, the viral damage and pneumonia takes them out. I don't see an internal conflict in the statements.
 
marsh

marsh

On TB every waking moment
Warm Wisconsin

Warm Wisconsin

Easy as 3.141592653589..
I don’t think these are being designed to help people recover. They are just quarantine areas to separate them from the public. I doubt the nurses in these facilities are getting out healthy.


marsh said:
What happens when the other cities start climbing in infections and they need their medical personnel back? Who is going to nurse all these folk in Wuhan?
Click to expand...
bw said:
If you aren't infected when you go in, you will be pretty quickly.
Click to expand...
 
bw

bw

Fringe Ranger
Warm Wisconsin said:
I don’t think these are being designed to help people recover. They are just quarantine areas to separate them from the public. I doubt the nurses in these facilities are getting out healthy.
Click to expand...

That's why they're using military. They need people who they can order to go in. These will be custodians more than nurses/medics. There's a reason for the bars on the windows.

I wonder what count they can pack in there before it's over. I was thinking 10-15,000, but after seeing the whole building I'm thinking much higher.
 
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