Ragnarok
On and On, South of Heaven
On his full show, Tucker goes into how a coronavirus outbreak in the US could get Bernie elected:
View: https://www.youtube.com/watch?v=s9ggifSGlZo
Well, the dude in charge the South Korean response to Kung Flu just committed suicide, so you know, it's probably just like the Flu.Does anyone else find it odd the Congressional brief will be classified? Me thinks it’s more to hide truths from the sheep.
On his full show, Tucker goes into how a coronavirus outbreak in the US could get Bernie elected:
View: https://www.youtube.com/watch?v=s9ggifSGlZo
Yeah, God put it THIS WAY: (YOU will live longer if you heed their advice!}I just called my daughter in Texas, with 10 month old twins, because this afternoon the prevailing thought has been "diapers."
She said she didn't believe in the prepping lifestyle, blah blah. I said that China is shut down, and she said she'll just get diapers someplace else. I told her it might not hurt to have some cloth and covers...I am NOT doing cloth diapers!
It was civil, as I know I have to bite my tongue, but I hung up thinking "girl, you're gonna be cutting up old t-shirts and rue the day you blew your mama off."
Yes, and this deserves further clarification. When we say it is a records system, a record keeping system, you could think it's just a dry thing played with by accountants after you are discharged from the hospital. While it is also that, it is something far more important, and why I actually mentioned it on this thread.
It is your LIVE chart while you are in the hospital. The nurse who asks you if you've been to China in the last 14 days enters that into EPIC. When he or she charts your vitals, they put in into EPIC. Your doctor then reads that information in their EPIC screen, and orders medications, surgeries, therapies, consultations, etc., using the EPIC system. In a word, it often determines the healthcare you're given, based on what is entered into it--which was also true of a paper chart.
Specifically here, say the nurse enters that you have been to China in the last 14 days, and you have a symptom of cough. It is EPIC that will now pop up a Best Practice Advisory. It is telling you in bright yellow on the screen that you need to put goggles on, put a mask on the patient, and get them into several kinds of isolation. This is the logic that I mentioned earlier in this thread that EPIC had released in January. Which I could see that my current client system put into production 2 Tuesdays ago.
So, if we discover much more accurate screening methods, effective isolation protocols, etc., it would be EPIC that would design and send out the code to implement that. Which is why we all benefit from it continuing to function. And not only hospitals. Most hospitals own scads of doctors practices. So if you go to your doctor's office, there's a good chance that they would be asking you the same questions about China and coughing, and getting that same determination from the EPIC clinic software, which I also train.
I wished that we were receiving factual updates on the number and locations of confirmed and suspected cases in the USA, if it is close to my location I will take my six weeks of saved vacation time from work and pull my teenagers from school. The question that I ask myself, when is it to late?
It they work for the people, they should tell the people.
Because, up to this point in time, there is absolutely NOTHING the CDC, WHO, or anyone else can do to mitigate the outcome other than ride it out and hope for the best. The Emperor and the bureaucratic lackeys do not want to be seen naked, even though they are, regarding this pandemic.
A plan has to have a predicated positive outcome... that's why there is no plan because there really isn't any mitigation that will work.
Yes, Cerner performs the same functions. Cerner HQ in KC, I think, so that would also be one to watch for. Just checked, Epic at 28%, Cerner 26% of US market. Maybe that's in dollars. I'd heard for years a figure of 75% Epic. Maybe that's in terms of population served. EPIC is in about 10 other countries, don't know about cerner. Would be interesting if their Corona algorithms are different in other countries. Don't have any info on that.EPIC is about 30% of the EHR market, I believe. Cerner is just as big, or bigger, I believe. But yes, they are all similar and do just what you say.
Well, the dude in charge the South Korean response to Kung Flu just committed suicide, so you know, it's probably just like the Flu.
I disagree. So far, the HHS/CDC visible actions have been avoidance - Stop certain travel, quarantine travelers, educate at-risk elders and those with co-morbidities in personal isolation and infection control strategies, . They have utterly failed in getting local testing activated to gauge the success of their strategy and to identify community hot spots where spread is happening. Then, school closures, event cancellations and the like could be employed.Because, up to this point in time, there is absolutely NOTHING the CDC, WHO, or anyone else can do to mitigate the outcome other than ride it out and hope for the best. The Emperor and the bureaucratic lackeys do not want to be seen naked, even though they are, regarding this pandemic.
A plan has to have a predicated positive outcome... that's why there is no plan because there really isn't any mitigation that will work.
Nothing is wrong. When you come BACK INTO the thread it'll be where it belongs in numerical order.
Do you have a link?Well, the dude in charge the South Korean response to Kung Flu just committed suicide, so you know, it's probably just like the Flu.
this coronavirus thing, I want to try to put this in perspective for you. It looks like the coronavirus is being weaponized as yet another element to bring down Donald Trump. Now, I want to tell you the truth about the coronavirus. (interruption) You think I’m wrong about this? You think I’m missing it by saying that’s… (interruption) Yeah, I’m dead right on this. The coronavirus is the common cold, folks.
The Drive-By Media hype of this thing as a pandemic, as the Andromeda strain, as, “Oh, my God, if you get it, you’re dead.” Do you know what the — I think the survival rate is 98%. Ninety-eight percent of people get the coronavirus survive. It’s a respiratory system virus. It probably is a ChiCom laboratory experiment that is in the process of being weaponized. All superpower nations weaponize bioweapons. They experiment with them. The Russians, for example, have weaponized fentanyl. Now, fentanyl is also not what it is represented to be.
If you watch cop shows, then you probably… Stick with me on this. If you watch cop shows, you probably believe that just the dust from a package of fentanyl can kill you if you’re in the same room with it. Not true. Not true. Even the cheap kind of fentanyl coming from China that’s used to spike heroin… They use fentanyl ’cause it’s cheap. It gives a quick hit, doesn’t last very long, which is really cool if you’re trying to addict people.
But it doesn’t kill people the way it’s projected on TV. It can if you OD on it. But inhaling a little fentanyl dust is not going to cause you to lose consciousness and stop breathing as they depict on cop shows. It’s dangerous. Don’t misunderstand. But it isn’t the way it’s portrayed in popular criminal TV shows, cop shows, and so forth and so on. The coronavirus is the same. It’s really being hyped as a deadly Andromeda Strain or Ebola pandemic that, “Oh, my God, is going to wipe out the nation. It’s going to wipe out the population of the world.”
The stock market’s down like 900 points right now. The survival rate of this is 98%! You have to read very deeply to find that number, that 2% of the people get the coronavirus die. That’s less than the flu, folks. That is a far lower death statistic than any form of influenza, which is an annual thing that everybody gets shots for. There’s nothing unusual about the coronavirus. In fact, coronavirus is not something new. There are all kinds of viruses that have that name. Now, do not misunderstand. I’m not trying to get you to let your guard down.
Nobody wants to get any of this stuff. I mean, you never… I hate getting the common cold. You don’t want to get the flu. It’s miserable. But we’re not talking about something here that’s gonna wipe out your town or your city if it finds its way there. This is a classic illustration of how media coverage works. Even if this media coverage isn’t stacked, even if this is just the way media normally does things, this is a hyped, panic-filled version. It’s exactly how the media deals with these things to create audience, readership, interest, clicks, what have you.
It originated in China in a little — well, not a little town. It’s a town that is 11 million people, Wuhan, China. One of the reasons they’re able to hype this is that the doctor what warned everybody about it came down with it and died. So if a doctor got it, “Oh, my God, Rush! A doctor got it? You can’t possibly be right if a doctor can’t protect himself.” He didn’t know what he was dealing with. He discovered it back in December. I’m telling you, the ChiComs are trying to weaponize this thing. Here’s the story on Russians and fentanyl.
Fentanyl is a very, very powerful opiate — and for those of you that haven’t had any experience with opiates, the people that get addicted to ’em take them and they get very euphoric. They kill pain. They do wonderful things. But they make you very, very euphoric. They act like speed. Other people take ’em, and they hate ’em. It makes ’em vomit, throw up, feel nauseous. It doesn’t do anything for ’em. They’re never gonna get addicted.
So in Moscow the Chechens, way back… I’m gonna go back now — what is it — maybe 10 years or longer. A bunch of Chechen rebels took over an opera house and had a bunch of Russian hostages in there and made all kinds of threats — and Putin, unbeknownst to anybody, had weaponized fentanyl. He’d turned it into a gas, an invisible gas. He just put it in the ventilation system of this opera house or whatever it was (I’m giving you the sketchy, short version of this) and everybody in there fell asleep and died. You know, in a drug overdose, you stop breathing.
That’s what… It slows down your respiratory system so much that you stop breathing. That’s what an OD is, and everybody in that place, including the Chechens — Pfft! — had no idea what happened to ’em. It’s not violent. You just fall asleep for unknown reasons at the amounts that Putin weaponized and put in there. If you take a normal dose of fentanyl that you get from a doctor in a hospital, it’s not gonna kill you, obviously. But the amount they weaponized — and up to this time, nobody had ever weaponized fentanyl.
Nobody had ever made it into an invisible, odorless, colorless gas, until it was discovered that the Russians had done it. Well, every nation is working on things like this, and the ChiComs obviously in their lab are doing something here with the coronavirus — and it got out. Some people believe it got out on purpose, that the ChiComs have a whole lot of problems based on an economy that cannot provide for the number of people they have. So losing a few people here or there is not so bad for the Chinese government.
There could be anything to explain this.
But the way it’s being used… I believe the way it’s being weaponized is by virtue of the media, and I think that it is an effort to bring down Trump, and one of the ways it’s being used to do this is to scare the investors, to scare people in business. It’s to scare people into not buying Treasury bills at auctions. It’s to scare people into leaving, cashing out of the stock market — and sure enough, as the show began today, the stock market — the Dow Jones Industrial Average — was down about 900 points, supposedly because of the latest news about the spread of the coronavirus.
And if you go deeper into China, you will see that all of the high-tech Silicon Valley firms are said to be terribly exposed. “They could be suffering a disastrous year. Why, you may not be able to buy a new iPhone of any model this whole year! Do you know that? Because the coronavirus is so bad that the factories may never open — and if they do, they may not be anywhere near full capacity.” So Apple may not be able to release any new product. You think that’s not gonna panic investors? It most certainly is.
So Apple is trying to do what they can to suggest that these rumors are not true. They got new products coming this year. But the tech media hates Apple. They love anti-Apple stories. They love anything that will let them report that Apple’s on its last legs. Of course, that’s not true. Warren Buffett came out today and said, “Apple is the best run company ever.” He’s a big stockholder. So people will say he’s biased about it. But the bias you have to pay attention to is how much money he invested. He got $36 billion in Apple stock that Berkshire Hathaway has.
They sold $800 million of Apple stock last week, and everybody said, “Oh, my God, he’s getting out!” No, he’s not. He’s got $36 billion. He sold $800 million. No big deal. He wanted to allocate it somewhere else. So this is… I think the coronavirus is an effort to get Trump. It’s not gonna work. It’s one of the latest in a long line of efforts that the Drive-By Media’s making to somehow say that Trump and capitalism are destroying America and destroying the world. Just keep in mind where the coronavirus came from.
It came from a country that Bernie Sanders wants to turn the United States into a mirror image of: Communist China. That’s where it came from. It didn’t come from an American lab. It didn’t escape from an American research lab. It hasn’t been spread by Americans. It starts out in a communist country. Its tentacles spread all across the world in numbers that are not big and not huge, but they’re being reported as just the opposite. Just trying to keep it all in perspective.
BREAK TRANSCRIPT
RUSH: Here’s Neil in Orlando. Great to have you on the program, sir. Hello.
CALLER: Hello, Rush. Man, I’m blessed to have the chance to talk to you. I cannot believe it. So you were talking about the coronavirus a little bit a while ago, and what’s the one thing that disappeared when the coronavirus came out?
RUSH: Well, let me see. What one thing? Just hang on. What disappeared? What disappeared? What disappeared? Oh, the protests in Hong Kong went away.
CALLER: Yes. That’s it.
RUSH: That’s a big…
CALLER: Yup.
RUSH: (whispering) Talent on loan from God.
CALLER: That sure is.
RUSH: That’s probably the big one, the protests in Hong Kong.
CALLER: That’s my take from it. I don’t know. I’ve got a friend over there that sends me stuff. But there’s a lot… We don’t want to start any conspiracy theories, but this will be my only time I ever get through to you ’cause I’ve been calling since ’92. But I just want to say about your talent on loan from God: Just in the time, I was on hold listening to you, and it got me to the point where I just wanted to say that Trump got no notice about Russian meddling like Sanders did. So why not? I wonder about that. When Carter was president, my first home buying — I was a first-time home buyer — the rate was 13.33%. I’ll never forget it, and that was a first-time homeowner!
RUSH: I know. I know.
CALLER: That was a deal!
RUSH: I know. I know.
CALLER: That was a deal at 13.33%!
RUSH: I bought my first shack, you know, at that time in Overland Park, Kansas. I had no business buying it. But everybody said, “You gotta buy! Don’t rent. You’re throwing money away if you rent.”
CALLER: Mmm-hmm.
RUSH: So, you know, my one time I became a conformist, it got me. I didn’t want to live in this shack! I never wanted to move into this shack. But it’s what I bought, so I had to move into the thing.
CALLER: And one more —
RUSH: I didn’t even want people to take me home. I didn’t want people to see this shack that I lived in. One day, we’re playing football — the Chiefs front office, the Royals front office — after the baseball season. Thursday afternoon flag football. George Brett’s playing and he offered to take me home. I said (chuckles), “No, George, I’m fine.” I didn’t want Brett to see where the shack was. So, yeah, 13% interest rates during Carter, and it was bad. Carter actually coined the term “malaise” to describe his own administration and its effect on the American economy!
We had “the misery index” and all of that.
But look, back to the coronavirus for just a second. That is true that the Hong Kong protests strangely subsided as the news of the coronavirus expanded — and I’ll tell you, it is a way… If you are a totalitarian government and you need to control your population, one of the best ways of doing it is unleashing something they think is a deadly disease and then you, as the dictator, have the “safety solutions.” You have the ability to round people up from their homes and take ’em to so-called health camps.
Be very leery of this, folks.
It probably is not what the media’s leading you to believe it is.
So every time I post, I have to leave the thread totally and then come back in and re-open it (and TRY to find my place) to see my post in its correct place?
This action doesn't align with the President's statements that everything is fine. Stampeding the sheeple is to be avoided at all costs.View attachment 183790
2 hr 28 min ago
White House submits $1.25 billion emergency request to address coronavirus
The White House has requested $1.25 billion in emergency funding to address coronavirus, as well as the ability to tap an additional $535 million in emergency funds already appropriated.
This letter, obtained by CNN, was sent to the Hill just a short time ago.
The Trump administration expects “to allocate at least $2.5 billion in total resources” for the response effort. Much of that would come from shifting already appropriated money from agency accounts.
White House submits $1.25 billion emergency request to address coronavirus
The White House has requested $1.25 billion in emergency funding to address coronavirus, as well as the ability to tap an additional $535 million in emergency funds already appropriated.www.cnn.com
Setting out there all alone ! make a bet we hear about a accidental fire on board while it is being cleaned and repaired. Before the fire could be brought under control the damage will be beyond repair, insurance pays the owner and she is sold for scrap..COVID-19: 188 Indonesians from World Dream cruise ship to be quarantined on uninhabited island
Budi Sutrisno
The Jakarta Post
Jakarta / Tue, February 25, 2020 / 06:25 am
A passenger wearing a facemask looks out from the cabin of the World Dream cruise ship at the Kai Tak cruise terminal in Hong Kong on Feb. 5. (AFP/Philip FONG )
Indonesia plans to evacuate 188 citizens working as crew members aboard the World Dream cruise ship to an island off Java amid concerns over the coronavirus, the government has said.
Coordinating Human Development and Culture Minister Muhadjir Effendy confirmed the repatriation plan on Monday following a meeting with President Joko “Jokowi” Widodo and Health Minister Terawan Agus Putranto at the State Palace.
He said the Dr. Soeharso naval hospital ship had headed to the sea off Riau Island on Sunday to pick up the Indonesians abroad the ship, which had anchored in international waters near the province’s Bintan Island to facilitate the transfer of the crew members.
Muhadjir said all of the Indonesian evacuees would be brought to Sebaru Island, which is part of the Thousand Islands regency in Jakarta, for observation.
“Sebaru is an […] uninhabited island,” Muhadjir said. “We consider it safe, because there are no inhabitants on the island and it has good facilities that we can just utilize.”
The World Dream has suspended its operations after docking in Hong Kong earlier this month, where it had spent days in quarantine at Kai Tak Cruise terminal after three Chinese nationals who had been onboard the ship between Jan. 19 and 24 tested positive for the virus, Reuters reported.
The ship’s 1,800 passengers had disembarked in Hong Kong on Feb. 9, leaving onboard some 1,814 crew members, including Indonesians, according to World Dream’s operator Dream Cruises.
Michael Goh, the Dream Cruises’ president, said that Hong Kong authorities had confirmed that all passengers and crew who sailed on the last voyage had gone through extensive health examinations, including body temperature checks.
All samples taken from the 1,814 crew members were negative of coronavirus and all passengers who had left the ship after the last trip had showed no symptoms associated with COVID-19 infection, Goh said in a statement as quoted by Antara.
He said Dream Cruises was working closely with local and regional authorities to facilitate the transfer and return of crew members given the diversity of their nationalities.
The repatriation of citizens aboard the World Dream came as the government planned the evacuation of dozens of Indonesian crew members of coronavirus-stricken Diamond Princess, who were still reported healthy after being quarantined with the ship for two weeks.
At least nine of 78 Indonesian crew members on the cruise ship tested positive for coronavirus alongside some 600 other infected people who had boarded the vessel.
Minister Terawan, however, said that in the meantime the government would focus on evacuating Indonesian citizens of the World Dream.
“We now concentrate on the World Dream, because that is the closest to us. This has the smallest risk. We always take the smallest risk first and we will manage to provide good quarantine facilities,” Terawan said.
Terawan said the government had decided to conduct the evacuation by sea in order to anticipate the spread of the virus if any was found.
“This medical aspect must be considered well, not emotionally. It must be one at a time, for the safety of the country since we are still in the green zone,” he added.
Indonesia has yet to confirm any coronavirus cases in the country to date. The far-flung virus, which has spread to some 30 countries, has killed more than 2,500 people in China and infected more than 77,000 worldwide.
===COVID-19: 188 Indonesians from World Dream cruise ship to be quarantined on uninhabited island - National - The Jakarta Post
Indonesia plans to evacuate 188 citizens working as crew members aboard the World Dream cruise ship to an island off Java amid concerns over the coronavirus, the government has said.www.thejakartapost.com
To be filed as an odd story.
===
.
This just in:
Researchers have recently started using lawyers instead of rats in their lab experiments. You don’t get so attached to them, and there are some things a rat just won’t do.
(Told to me by a lawyer . . . )
I'm not saying that Rush is wrong--he's probably right on one level--but unless the entire world's media is freaking out their countries in order to destroy Donald Trump as well, the reactions of other countries' governments just does not line up with this being not that big of a deal. I mean, don't get me wrong, I'm sure that this was planned by someone, somewhere, and they are making full use of this crisis, but that doesn't mean that they aren't willing to kill off a whole bunch of us to do it.Oliver Darcy
@oliverdarcy
Rush Limbaugh: “It looks like the coronavirus is being weaponized as yet another element to bring down Donald Trump. Now, I want to tell you the truth about the coronavirus. ... The coronavirus is the common cold, folks.” https://rushlimbaugh.com/daily/2020/02/
...Certain the lord understands shutting down in person services during pandemics...
Reuters
@Reuters
4m
South Korea to test 200,000 members of church at centre of coronavirus outbreak https://reut.rs/2VlffYO
View: https://twitter.com/Reuters/status/1232156773706084353?s=20
Vincent Lee
@Rover829
Reuters: KOREAN AIR SAYS ONE CABIN CREW MEMBER TESTED POSITIVE FOR CORONAVIRUS
Eva Fu @EvaSailEast 28s29 seconds ago
An internal document obtained by@EpochTimes revealed 800+ police officers and families have#coronavirus in#HubeiProvince - yet another challenge for Chinese authorities trying to contain the outbreak
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study |
Implications of all the available evidence The mortality of critically ill patients with SARS-CoV-2 pneumonia at 28 days is considerable. The survival time of non-survivors is likely to be within 1–2 weeks after ICU admission. Older patients (>65 years) with comorbidities and ARDS are at increased risk of death. The severity of SARS-CoV-2 pneumonia poses great strain on critical care resources in hospitals, especially if they are not adequately staffed or resourced. Outcomes The primary outcome was 28-day mortality after ICU admission. Secondary outcomes were incidence of SARS-CoV-2-related acute respiratory distress syndrome (ARDS). ARDS and shock were defined according to the guidance of WHO for novel coronavirus disease 2019 (COVID-19). 6 Acute kidney injury was identified on the basis of serum creatinine. 11 Cardiac injury was diagnosed if the serum concentration of hypersensitive cardiac troponin I (hsTNI) was above the upper limit of the reference range (>28 pg/mL), measured in the laboratory of Jin Yin-tan Hospital. Statistical analysis The aim of this study is to report the clinical courses and clinical outcomes of critically ill patients being cared for in the hospital during the study period. There were, therefore, no formal hypotheses being implemented to drive the sample size calculation and we included the maximum number of patients who met the inclusion criteria. We expressed descriptive data as mean (SD) or median (IQR) for continuous variables and number (%) for categorical variables. We assessed differences between survivors and non-survivors using two-sample t test or Wilcoxon rank-sum test depending on parametric or non-parametric data for continuous variables and Fisher's exact test for categorical variables. We used a Kaplan-Meier plot for survival data. Tests were two-sided with significance set at α less than 0·05. The Stata/IC 15.1 software (StataCorp, College Station, TX, USA) was applied for all analyses. Results By Jan 26, 2020, 710 patients had been admitted to Wuhan Jin Yin-tan hospital with confirmed SARS-CoV-2 pneumonia, of whom 658 (93%) were considered ineligible, including three patients who had cardiac arrest immediately after admission. 52 (7%) critically ill patients were included in this study (figure 1). All patients were residents of Wuhan City and were transferred from other hospitals. The mean age was 59·7 years (SD 13·3), and 27 (52%) were older than 60 years (table 1). 35 (67%) patients were men. 17 (33%) patients had a history of exposure to the Huanan seafood market, and 10 (19%) had exposure to patients with confirmed or highly suspected SARS-CoV-2 infection. 21 (40%) patients had chronic diseases, including cerebrovascular diseases in seven (13·5%) patients, all of whom died at 28 days. All patients had bilateral infiltrates on chest x-ray. Discussion We report on 52 critically ill patients with confirmed SARS-CoV-2 infection, characterised by severe hypoxaemia. 32 (61·5%) of critically ill patients had died at 28 days. Of all included patients, 37 (71%) required mechanical ventilation and 35 (67%) had ARDS. Since no specialised medication to treat SARS-CoV-2 infection has been identified at this time, the mainstay of treatment has been supportive care. Patients are being treated in isolation, and their close contacts are being quarantined. For non-critically ill patients, close follow-up is likely to be sufficient to manage the disease. 1 , 2 , 3 For critically ill patients, however, aggressive treatments and intensive care are needed. To our knowledge, this is the first study to characterise critically ill patients infected by SARS-CoV-2. In three previously published studies of crtically ill patients, the patient numbers were too small to summarise the characteristics and mortality of these patients with SARS-CoV-2 pneumonia. 1 , 2 , 5 Like SARS-CoV and Middle Eastern respiratory syndrome (MERS)-CoV, SARS-CoV-2 is a coronavirus that can be transmitted to humans, and these viruses are all related to high mortality in critically ill patients. 12 However, the mortality rate in patients with SARS-CoV-2 infection in our cohort is higher than that previously seen in critically ill patients with SARS. In a cohort of 38 critically ill patients with SARS from 13 hospitals in Canada, 29 (76%) patients required mechanical ventilation, 13 (43%) patients had died at 28 days, and six (16%) patients remained on mechanical ventilation. 8 17 (38%) of 45 patients and 14 (26%) of 54 patients who were critically ill with SARS infection were also reported to have died at 28 days in a Singapore cohort 13 and a Hong Kong cohort, 14 respectively. The mortality rate in our cohort is likely to be higher than that seen in critically ill patients with MERS infection. In a cohort of 12 patients with MERS from two hospitals in Saudi Arabia, seven (58%) patients had died at 90 days. 15 Since the follow-up time is shorter in our cohort, we postulate that the mortality rate would be higher after 28 days than that seen in patients with MERS-CoV. The fundamental pathophysiology of severe viral pneumonia is severe ARDS. Men and people of an older age (>65 years) are more likely to develop ARDS than women or those of a younger age. 16 Therefore, it is reasonable that the mortality at 28 days of severe SARS-CoV-2 pneumonia is similar to the mortality of severe ARDS, which is near 50%. 17 With a substantial increase in the number of critically ill patients infected by SARS-CoV-2, more provisional ICUs are being established in Wuhan, China. Qualified specialists are coming to Wuhan from other provinces of China and are currently working in these provisional ICUs, fever clinics, and newly constructed hospitals. 18 As the clinical capacity to treat patients improves, the mortality of critically ill patients with SARS-CoV-2 pneumonia is expected to decrease. As mentioned in previous studies, nearly 70% of patients infected by SARS-CoV-2 were men. 1 , 2 The patients are older in our study than in previous studies. 1 , 2 We observed that non-survivors were older than survivors. Based on previous studies, evidence suggests that older, male patients are the most susceptible to SARS-CoV-2 infection, 2 which is supported by our data. As previously reported, patients with a history of cerebrovascular disease are at increased risk of becoming critically ill or dying if they have SARS-CoV-2 infection. 2 , 5 In our cohort, fever is the most common symptom in patients with SARS-CoV-2 pneumonia, which is in accordance with previous studies, but not all patients had fever. 1 , 2 , 5 We also found that fever was not detected at the onset of illness in six (11·5%), and that it was in fact detected 2–8 days later. The delay of fever manifestation hinders early identification of patients infected with SARS-CoV-2—if patients are asymptomatic identification of suspected cases is more difficult. 19 , 20 The median duration from onset of symptoms to radiological confirmation of pneumonia was 5 (3–7) days, meaning that early or repeated radiological examinations are useful in screening patients with SARS-CoV-2 pneumonia. 4 As for laboratory tests, lymphocytopenia occurred in more than 80% of critically ill patients in our cohort. Lymphocytopenia is a prominent feature of critically ill patients with SARS-CoV infection because targeted invasion by SARS-CoV viral particles damages the cytoplasmic component of the lymphocyte and causes its destruction. 21 Additionally, lymphocytopenia is also common in the critically ill patients with MERS infection, which is the result of apoptosis of lymphocytes. 22 , 23 Therefore, we postulate that necrosis or apoptosis of lymphocytes also induces lymphocytopenia in critically ill patients with SARS-CoV-2 infection. In a previous study, mainly in non-critical patients infected with SARS-CoV-2, 35% of patients had only mild lymphocytopenia, 2 suggesting that the severity of lymphocytopenia reflects the severity of SARS-CoV-2 infection. Mechanical ventilation is the main supportive treatment for critically ill patients. The PaO2/FiO2 ratio was lower in our patients than in patients admitted to Zhongnan Hospital. 5 The substantial difference in PaO2/FiO2 ratio between survivors and non-survivors in our study, indicates this ratio is associated with the severity of illness and thus prognosis. Barotrauma seems less severe in patients with SARS-CoV-2 infection who are being mechanically ventilated than that seen in mechanically ventilated patients with SARS-CoV. In our study, barotrauma occurred in only one (2%) patient, who had been hospitalised for nearly 1 month, and they are currently on a ventilator and receiving ECMO. In patients with SARS, barotrauma occurred in about 25% of patients on mechanical ventilation. 14 The lower occurrence of barotrauma in our cohort is probably related to the widely accepted strategy of protective ventilation in mainland China. 24 At the same time, prone position and ECMO have been used to treat patients with SARS-CoV-2 pneumonia. Without solid evidence, nearly half of the patients were given antiviral agents, and more than half were given intravenous glucocorticoids. Patients treated with lopinavir were from an ongoing clinical trial registered on Chinese Clinical Trial Registry (ChiCTR2000029308). Remdesivir was given to the first patients with SARS-CoV-2 pneumonia in the USA. 4 Trials on remdesivir are about to recruit both mild to moderate patients (NCT04252664) and severe patients (NCT04257656) infected with SARS-CoV-2. Although, intravenous glucocorticoids were commonly used in patients with severe SARS or MERS pneumonia, their efficacy remains controversial and their use to treat SARS-CoV-2 infection is also controversial. 5 , 25 An ongoing clinical trial (NCT04244591) might shed some light on the safety and efficacy of these drugs as treatment. This study has several limitations. First, only 52 critically ill patients were included. However, the population from which they were sampled was much larger than that of the three studies previously published. 1 We included all the critically ill patients being cared for in the ICU of Jin Yin-tan hospital who met the inclusion criteria. Due to the exploratory nature of the study, which was not driven by formal hypotheses, the sample size calculation was waived. Instead, we hope that the findings presented here will encourage a larger cohort study or potentially some randomly controlled trials. Second, some specific information from the ICU was missing, such as mechanical ventilation settings. The data on radiographical examination, supportive treatment, living status, and the duration from ICU admission to death, however, are indisputable. Third, this is a retrospective study. The data in this study permit a preliminary assessment of the clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia. Further studies are still needed. In conclusion, the mortality of critically ill patients with SARS-CoV-2 pneumonia is high. The survival term of the non-survivors is likely to be within 1–2 weeks after ICU admission. Older patients (>65 years) with comorbidities and ARDS are at increased risk of death. The severity of SARS-CoV-2 pneumonia poses great strain to hospital critical care resources, especially if they are not adequately staffed or resourced. |
Getting a late start today, took over an hour to catch up.
I want to comment on this because it is something very basic about COVID that is getting lost in the pages of posts.
When you have a virus that is spread when the person is asymptomatic, and can be asymptomatic and contagious for 2 weeks or more when no one even knows they are sick- when that virus can be spread through the air, through fomites left on surfaces, and in public bathrooms - when tests and temperature checks aren't picking up the disease in people with symptoms, let alone those without them yet - the ONLY way to mitigate this virus is to do a complete and total lockdown. That's why China went that route as soon as they got an outbreak in a city. (more evidence pointing to them knowing exactly what they were dealing with very early on in this process - most likely because as it was not natural). That's why Iran and Italy are going that route with reported cases under 100..... That is the ONLY way to control this. And the CDC and the Trump Admin know that that will never fly in the USA. No one is going to let Trump do a lockdown in a city unless people are dying in the street, and by then, it's too late.
Nothing short of a complete lockdown is stopping this disease. They all know it. And they will never let Trump do it, so we're all going to be exposed.
OTOH, there are things they can be doing and hopefully they are doing them. Figuring out how to do food distribution door to door or letting a few people out at a time if they do lockdown a city, (will they take over your local COSTCO/SAMS/Grocery chain warehouse and gather all food for gov't distribution?), how they will enforce martial law if it comes to that, how to manage keeping the lights and water and sewers going, and the TV and internet and cellphones to entertain the masses while they are stuck in their homes, what to do with the people who can't get their meds, especially those who need them to live and those who need them to stay sane and not become a danger to themselves or those they are locked down with, how will they recover dead bodies who aren't in a hospital and what till they do with them when they have them. These are things that need to be planned - we should be on a war planning footing now, and for the last month and a half. Hopefully they have been using this time wisely so that if they need to move to quarantining and locking down cities it goes as smoothly as possible.
HD